，片岡 隆浩Kiyonori Yamaoka, Takahiro Kataoka岡山大学学術研究院保健学域Faculty of Health Sciences, Okayama University
トロンおよび子孫核種の生体作用に関しては科学的解明が不十分なままであるが，ICRPからラドンのそれより強いことが示され関心が高まっている。このため，関連研究成果の一部を概説した。その結果，ラドン摂取と同様，トロン摂取も微量の活性酸素の発生に伴う生理的刺激作用により抗酸化機能などを亢進させ，酸化ストレス関連疾患の症状を緩和することが示唆できた。また，この作用の至適濃度は放射能特性の差異によりトロン摂取の方が低い領域で現れることもわかった。
The scientific evidence for the medical application of thoron, an isotope of radon, remains to be insufficient internationally. In addition, the ICRP reported that thoron progeny nuclides show higher radiobiological effects than radon progeny nuclides. For this reason, we outlined some of the research results that we have so far reported the biological effects of thoron and comparison with those of radon. As a result, we were able to suggest that, like radon ingestion, thoron ingestion enhances antioxidant function through physiological stimulation caused by the generation of trace amounts of active oxygen, thereby alleviating the symptoms of oxidative stress-related diseases. In addition, we found that thoron appears in a range with a lower optimal inhalation concentration than radon due to the difference in radioactivity characteristics, which is consistent with the ICRP report.
Key words: thoron; radon; biological effects; therapeutic indications; antioxidant function; optimal concentration
© Japan Radioisotope Association 2025. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)© Japan Radioisotope Association 2025. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)
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