兵庫医科大学薬学部School of Pharmacy, Hyogo Medical University
本研究では天然放射性核種である40K由来のβ−線計測を利用した輸液中カリウム濃度の定量法を検討した。輸液試料40 mL中のカリウムイオンを陽イオン交換樹脂3 gへ吸着させ，グルコース等の共存成分を除去した。ラジオルミノグラフィにて種々の輸液中カリウム濃度を計測し，40及び60 mEq/Lの各種輸液において真度95–105%の範囲で定量可能であることを見出した。本法はカリウム輸液による医療事故防止への応用が期待される。
In this study, we investigated a method for quantifying K+ concentration in infusion solutions using β-ray measurement derived from the naturally occurring radionuclide 40K. K+ in 40 mL of infusion samples were adsorbing onto 3 g of medical cation exchange resin, and enabling the removal of coexisting components such as glucose from the infusion samples. K+ concentration in various infusion solutions was measured using radioluminography, and the method achieved quantitative accuracy within 95–105% of the nominal concentrations containing 40 or 60 mEq/L potassium. This method is expected to be applicable for preventing medical accidents caused by potassium-containing infusions.
Key words: potassium-40; cation exchange resin; infusion solution; radioluminography; potassium concentration
© Japan Radioisotope Association 2026. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)© Japan Radioisotope Association 2026. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)
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