4πβ–γ同時計数による177Lu放射能絶対測定Activity Standardization of 177Lu with 4πβ–γ Coincidence Counting Method
産業技術総合研究所National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology
産業技術総合研究所National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology
177Luが含まれる放射性薬剤が,核医学治療に用いられている。このため,産業技術総合研究所計量標準総合センターにおいて,177Luの放射能が4πβ–γ同時計数により絶対測定された。113 keVと208 keVのγ線を用いてβ線との同時計数が行われた。本測定により,日本における177Luの放射能標準が確立できた。
Radiopharmaceuticals containing 177Lu are used in nuclear medicine therapy. The National Metrology Institute of Japan has therefore standardized the activity of 177Lu by 4πβ–γ coincidence counting using gamma-rays with energies of 113 and 208 keV. The traceability of activity measurements for 177Lu in Japan is ensured by this standardization.
Key words: Lutetium-177; standardization; 4πβ–γ coincidence counting; theranostics; prostate cancer
© Japan Radioisotope Association 2025. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)© Japan Radioisotope Association 2025. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)
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