1 京都大学大学院医学研究科人間健康科学系専攻Human Health Sciences, Graduate School of Medicine, Kyoto University
2 広島大学原爆放射線医科学研究所Research Institute for Radiation Biology and Medicine, Hiroshima University
再生医療の活性化に伴い，幹細胞などの再生医療製品の国際搬送の必要性が高まっている。現状の国際搬送は航空機搬送が主体であるが，空港におけるセキュリティ検査のX線や宇宙放射線による被ばくの影響が懸念される。日本発着国際便による1回の輸送で宇宙放射線が細胞核にヒットする確率は高くはないが，細胞死や癌化といった問題だけでなく，幹細胞に求められる分化能に対する影響を否定することができない。そこで，航空機輸送に伴う低線量被ばくが与える影響の解明と併せて，宇宙放射線を効果的に遮蔽できる搬送容器や搬送システムの開発が必要である。
As regenerative medicine becomes more active, the need for international transportation of regenerative medical products such as stem cells is increasing. Currently, international transport is mainly by air, but there are concerns about the effects of exposure to X-rays during security inspections at airports and cosmic radiation. Although the probability of cosmic radiation hitting cell nuclei during a single international flight to/from Japan is not high, it is necessary to minimize not only cell death and malignant transformation, but also the effects on the differentiation potential required of stem cells. Therefore, it is necessary to study the effects of low-dose radiation exposure during air transport and to develop transport containers and systems that can effectively shield cells from space radiation.
Key words: regenerative medicine; air transportation; shielding; cosmic radiation; radiation exposure
© Japan Radioisotope Association 2023. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)© Japan Radioisotope Association 2023. This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/)
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