Online ISSN: 1884-4111 Print ISSN: 0033-8303
Radioisotopes 68(10): 723-729 (2019)

特集Special Issues

8.2.6 炭素線治療における分割照射効果8.2.6 Fractionation in Carbon-Ion Therapy

群馬大学重粒子線医学研究センター Gunma University Heavy Ion Medical Center ◇ 371–8511 群馬県前橋市昭和町3–39–22 ◇ 3–39–22 Showa-machi, Maebashi, Gunma 371–8511, Japan

発行日:2019年10月15日Published: October 15, 2019


In carbon-ion therapy, superiority of the physical dose distribution leads to a reduction in the number of fractions or may even allow hypofractionation. Several clinical trials are currently underway to evaluate the clinical effect of fractionated carbon-ion therapy. However, the biological effects of fractionation in carbon-ion beams hasn’t been investigated in detail. In this review, we will summarize the meaning of the fractionation and introduce mainly about previous study and our knowledge in the biological effects of fractionation using HIMAC.

Key words: HIMAC (Heavy Ion Medical Accelerator in Chiba); linear-quadratic (LQ) model; hypofractionation

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