Online ISSN: 1884-4111 Print ISSN: 0033-8303
Radioisotopes 68(6): 377-382 (2019)

特集Special Issues

4.2.3 生物効果モデルに関わる新たな展開より高い治療効果の実現に向けた取り組み4.2.3 New Evolutions in Biological ModelingFor Improved Clinical Effectiveness

量子科学技術研究開発機構放射線医学総合研究所物理工学部Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology ◇ 263–8555 千葉県千葉市稲毛区穴川4–9–1 ◇ 4–9–1 Anagawa, Inage-ku, Chiba 263–8555, Japan

発行日:2019年6月15日Published: June 15, 2019


Recently, advanced treatment techniques such as respiratory gating, scanning irradiation, and intensity-modulated particle therapy have been developed and utilized worldwide. To make the best use of these techniques and increase the clinical effectiveness of charged-particle therapy, it is important to investigate the effects of repair and oxygen enhancement ratio (OER) on biological effectiveness of the therapy. If the effects are non-negligible, the effects should be considered in clinical RBE system. In this chapter, recent efforts to investigate these effects are briefly overviewed.

Key words: HIMAC (Heavy Ion Medical Accelerator in Chiba); repair; OER (Oxygen Enhancement Ratio); multi-ion therapy

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