Online ISSN: 1884-4111 Print ISSN: 0033-8303
Radioisotopes 68(6): 367-375 (2019)

特集Special Issues

4.2.2 炭素線治療のための生物モデルの進展と検出器の開発4.2.2 Development of Biological Models and Related Detectors for Ion-beam Therapy

量子科学技術研究開発機構放射線医学総合研究所物理工学部Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology ◇ 263–8555 千葉市稲毛区穴川4–9–1 ◇ 9–1 Anagawa-4, Inage-ku, Chiba, Chiba 263–8555, Japan

発行日:2019年6月15日Published: June 15, 2019


Carbon beams, used for cancer therapy, are characterized by rapidly changing radiation qualities as well as dose. This is significantly different from ordinary types of radiation. As a result, the biological effect and treatment efficacy change and actually increase around an end point. Therefore, a reliable biological model is indispensable for safe and efficient therapy. This article describes the development and character of the NIRS biological model, and compares it with the GSI biological model. Further development of various detectors for measuring the radiation qualities is outlined.

Key words: HIMAC (Heavy Ion Medical Accelerator in Chiba); RBE (Relative Biological Effectiveness); LET (Linear Energy Transfer); dose

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