Online ISSN: 1884-4111 Print ISSN: 0033-8303
Radioisotopes 68(6): 361-366 (2019)

特集Special Issues

4.2.1 日本における炭素線治療の開始に向けて拡大ブラッグピークの設計4.2.1 History of Biophysical Development for Carbon Therapy at NIRS

大阪重粒子線センターOsaka Heavy Ion Therapy Center ◇ 540–0008 大阪府大阪市中央区大手前3–1–10 ◇ 3–1–10 Otemae, Chuo-ku, Osaka City, Osaka 540–0008, Japan

発行日:2019年6月15日Published: June 15, 2019


A carbon-ion clinical study began in June of 1994. In order to apply carbon beams to radiation therapy, we must modify the pristine carbon beam according to a real situation of clinical treatments. In this section, we describe how we had prepared for heavy ion therapy, especially how we developed the design of the Spread-Out Bragg Peak.

Key words: HIMAC(Heavy Ion Medical Accelerator in Chiba); carbon therapy; RBE(Relative Biological Effectiveness); clinical dose; biological dose; physical dose; LET(Linear Energy Transfer); LQ model

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